Amide library created at speed with machine learning and stopped-flow chemistry

A team of scientists based in Sweden and the UK has developed a synthetic screening method that uses stopped-flow chemistry and machine learning to accelerate drug discovery through diversity-oriented synthesis.1 Stopped-flow chemistry is an alternative method to traditional batch and continuous flow processes. By arresting the flow of reacting materials within the system, the platform […]

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Class still a barrier to success in academia, survey finds

Is academia becoming a ‘genteel hobby’ once more, rather than a way to make a living? That is the concern of one respondent to the first University and College Union (UCU) survey on social class in post-16 education. While some from working-class backgrounds may be put off entering the sector by low pay and job […]

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Core–shell nanomaterial enhances electrochemical ammonia synthesis

Researchers in China have devised electrocatalytic nanomaterials consisting of vanadium oxide cores within a vanadium nitride shell for reducing nitrogen to ammonia. The team found they could tune the nanomaterials’ core-shell structure to optimise the process’ efficiency and yield. As one of the most produced inorganic chemicals, ammonia plays an important role in agriculture (for […]

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The Afghan organic chemist who can’t return home

Abdul* fled Afghanistan with his family age six, and grew up in Iran as a poor refugee, but, against all the odds, he won national science competitions and became one of the first Afghans to study chemistry at an Iranian university. After returning to his homeland and using his expertise to better the country for […]

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Photochemistry enables safer method for reprocessing plutonium and uranium mixtures

Photochemistry can be used to separate plutonium and uranium, new research shows. By showing that photochemistry can replace harsh redox agents during actinide separations, the work could benefit nuclear processing facilities and environmental remediation efforts. The redox chemistry of the actinides plays a vital role in the chemistry of separating them. The near overlapping energies […]

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Beinecke Library Redux: From Bad to Worse!

On Monday I wrote a quick blogpost on the not insubstantial errors in the description of one of Galileo’s lunar washes posted on the Beinecke Library blog. I was somewhat pleasantly surprised when with a day the description had been heavily edited, romovi9ng all the sections that I had criticised even if no acknowledgement was […]

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Nobel prize rewards click chemistry and bioorthogonal reactions

This year’s chemistry Nobel prize is shared equally between the click chemistry pioneers Barry Sharpless and Morten Meldal, and Carolyn Bertozzi, who shaped the field of bioorthogonal chemistry. For Sharpless, this is his second chemistry Nobel prize – he’s only the second person after Frederick Sanger to receive two chemistry prizes. ‘I’m absolutely stunned, I’m […]

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