Seventy-Year Journey Wraps Up with Unveiling of Streamlined Route to Essential Reactive Intermediate

Seventy-Year Journey Wraps Up with Unveiling of Streamlined Route to Essential Reactive Intermediate

Since ortho-quinodimethane was initially suggested in 1957, it has persisted as a difficult yet significant molecule for the synthesis of intricate compounds present in natural substances and pharmaceuticals. However, two chemists from Japan have now discovered a more straightforward method to produce this reactive intermediate from widely accessible chemicals. The Diels–Alder reaction utilizes reactive dienes […]

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DNA Barcoding in Drug Discovery Screens Might Miss Possible Treatments

DNA Barcoding in Drug Discovery Screens Might Miss Possible Treatments

Recent studies indicate that drug discovery initiatives that depend heavily on DNA-encoded chemical libraries might be missing numerous viable drug candidates. These libraries assign a unique DNA sequence to each molecule, similar to a barcode, allowing researchers to examine extensive numbers of compounds at the same time. These large datasets are often crucial for training […]

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Grasping the Objectives and Aims of the Synthetic Human Genome Initiative

Grasping the Objectives and Aims of the Synthetic Human Genome Initiative

It has been just over two decades since the human genome project was finalized, which decoded the chemical structure of (almost) our entire genetic code and set the stage for numerous medical innovations, along with gene-editing technologies. After reading and editing the genetic blueprint, researchers now aspire to compose it. Recent strides in developing the […]

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US Charity Launches $100 Million Green Chemistry Initiative

US Charity Launches $100 Million Green Chemistry Initiative

The Gordon and Betty Moore Foundation, a distinguished private philanthropic entity located in California, is poised to allocate nearly $100 million (£73 million) towards an innovative green chemistry project. This trailblazing seven-year undertaking signifies the foundation’s inaugural investment centered on chemistry and will be led by the esteemed green chemistry pioneer Paul Anastas. Anastas, a […]

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Rethinking the Influence of Oxidants in Methane Pyrolysis

Rethinking the Influence of Oxidants in Methane Pyrolysis

Incorporating minimal quantities of oxidants into methane pyrolysis has demonstrated a notable increase in carbon and hydrogen outputs while maintaining catalyst performance, challenging established notions regarding the process. Traditionally, methane pyrolysis entails the decomposition of methane without oxygen, employing a catalyst to reduce the temperature and speed up the reaction, thereby offering a promising low-emission […]

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Synthesis and Characterization of Lanthanide-Carbon Triple Bond

Synthesis and Characterization of Lanthanide-Carbon Triple Bond

A major advancement in lanthanide chemistry has been realized with the establishment of a lanthanide–carbon triple bond for the first instance. This bond, specifically between cerium and carbon, exists within a C₈₀ fullerene cage, representing a significant milestone given the historic difficulties in isolating lanthanide–ligand multiple bonds. In the last twenty years, scientists have made […]

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Aria Launches Quest for New Leader After Ilan Gur's Departure

Aria Launches Quest for New Leader After Ilan Gur’s Departure

The UK’s Advanced Research and Invention Agency (Aria) is currently seeking a new leader, following the announcement from its chief executive, Ilan Gur, that he plans to resign. Having led the agency since its establishment three years ago, Gur’s exit signifies a crucial juncture for Aria. Inspired by the US Defense Advanced Research Projects Agency, […]

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