"Panthers Showcase Tenacity in the Face of Escalating Brain Disease Risks"

“Panthers Showcase Tenacity in the Face of Escalating Brain Disease Risks”


### New Research Brings Encouragement for Florida Panthers Amidst Increasing CWD Worries

The Florida panther, a unique subspecies of the puma and a prominent emblem of Florida’s natural heritage, remains at the forefront of conservation initiatives. With only an estimated 120-230 adults left in the wild, any new threat to their existence is alarming. Nevertheless, a recent study from the University of Central Florida sheds light on a positive development: Florida panthers seem to have a natural defense against a lethal disease that has wreaked havoc on ecosystems throughout North America.

### Chronic Wasting Disease: An Escalating Danger

In June 2023, chronic wasting disease (CWD) was discovered for the first time among Florida’s white-tailed deer. This terminal brain affliction, triggered by malformed proteins known as prions, impacts deer, elk, and other similar species. It is transmitted through bodily fluids such as saliva and urine, with symptoms—including weight loss, shifts in behavior, and neurological degradation—being particularly harmful.

The emergence of CWD in Florida raised significant alarm among conservationists. Since deer are the main prey of the Florida panther, it prompted inquiries about whether eating infected deer could endanger the already vulnerable panthers. Prion diseases, including CWD, are recognized for their capability to cross species lines under certain conditions, spurring researchers to confront this urgent issue.

### UCF’s Genetic Research: Comfort for Panthers

A group of scientists at the University of Central Florida (UCF) explored whether Florida panthers had an increased risk of contracting prion disease from contaminated prey. Their findings, which were recently shared in the *Journal of Wildlife Diseases*, examined the genetic profile of Florida panthers, focusing on variations of a prion-linked gene known to affect vulnerability to such diseases.

The UCF research team, led by Professor Bob Fitak and undergraduate researcher Elizabeth Sharkey, discovered that Florida panthers possess genetic characteristics akin to other North American pumas regarding prion susceptibility. This is a notable discovery since pumas in different areas have been known to consume prion-infected deer without falling ill.

“We sequenced the DNA of this gene in several Florida panthers, and we demonstrated that Florida panthers are not more or less susceptible than other puma populations in North America,” Fitak mentioned. “This is encouraging news. We understand that elsewhere in the country, pumas can consume infected deer and remain healthy.”

Sharkey continued by highlighting an unanticipated genetic aspect found during the research. “Our study revealed a new Central American prion allele that was likely introduced into the Florida panther population before the well-known genetic rescue in 1995. Fortunately for Florida panthers, this new allele does not seem to alter susceptibility to prion disease.”

### A Conservation Triumph: The Genetic Rescue of 1995

Understanding the recovery of the Florida panther population hinges on a crucial conservation achievement from the 1990s. By the early 1990s, the species had dwindled to merely 20-30 specimens, leading to extreme inbreeding and deteriorating genetic viability. To remedy this, wildlife specialists brought in pumas from Texas to enhance genetic diversity—an approach referred to as “genetic rescue.”

This initiative proved to be highly successful, enhancing both the number of individuals and overall genetic health of the panther population. The presence of the Central American prion allele, as noted in the UCF research, likely resulted from these genetic introductions.

While Florida panthers continue to encounter threats such as habitat loss, vehicle accidents, and other diseases, this study emphasizes the strength derived from their genetic background. By revealing that they are not disproportionately susceptible to CWD, the findings reinforce the significance of previous conservation efforts and offer optimism for the species’ future.

### Glossary of Key Terms

– **Prion**: A type of misfolded protein responsible for fatal brain diseases in animals and humans. Prions replicate by triggering normal proteins to fold incorrectly.
– **Chronic Wasting Disease (CWD)**: A fatal disease caused by prions affecting deer and elk, resulting in cognitive decline and eventual death.
– **Genetic Rescue**: A conservation strategy involving the introduction of individuals from external populations to boost genetic diversity in endangered species.
– **Allele**: Different versions of the same gene, which can affect traits, including susceptibility to diseases caused by prions.

### Implications for Conservation

The UCF study underscores the significance of proactive conservation strategies and genetic research in safeguarding endangered species. The results indicate that, although chronic wasting disease poses a serious ecological challenge, it does not represent an immediate direct threat to Florida’s panther population. This finding allows conservationists to devote more resources to other pressing issues, such as habitat fragmentation and human-driven efforts to support sustainable populations.