An unprecedented four-electron carbon intermediate has been isolated and characterised by researchers in the US. The team used a two-step approach to remove the non-bonding electrons from a stable carbene intermediate to create a crystalline doubly oxidised carbene. Carbenes were first discovered at the beginning of the 20th century but their extreme reactivity made them […]
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The 2023 Nobel prize in physiology or medicine has been awarded jointly to Katalin Karikó and Drew Weissman for research that was critical in the development of mRNA vaccines against Covid-19. The Nobel committee honoured Hungarian-born biochemist Karikó and US immunologist Weissman ‘for their discoveries concerning nucleoside base modifications that enabled the development of effective […]
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