Water microdroplet chemistry is contentious, here’s why

When a team led by Stanford University’s Richard Zare announced in 2019 that sprays of microscopic water droplets spontaneously produce hydrogen peroxide it attracted both excitement and scepticism. These days Zare is doubling down, arguing that many applications for catalysis – including nitrogen fixing, converting methane to methanol and transforming carbon dioxide into valuable chemicals […]

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First GPT-4-powered AI lab assistant independently directs key organic reactions

US-based computational chemists have developed an end-to-end artificial intelligence (AI) research assistant called Coscientist, which takes on time-consuming tasks like deciding reaction conditions and writing code for automated systems. Gabe Gomes’s team at Carnegie Mellon University in Pittsburgh, adapted the GPT-4 large language model (LLM) that powers the paid-for version of ChatGPT to perform different […]

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Machine learning identifies promising antibacterial ruthenium-based drug candidates

A machine learning model has been created that can identify ruthenium-based antibiotic drug candidates. With a small training set of just 288 antibacterial organometallic compounds, the algorithm scanned millions of structures, selecting the most active against resistant bacteria. The most promising candidates were tested and showcased almost six times greater antibiotic activity than the training […]

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Bonding nanoparticles to rubber increases material’s fatigue resistance sixfold

Strategically embedding rigid particles around long polymer chains can dissipate stress in rubber and increase the fatigue threshold sixfold, researchers in the US have shown. This potentially opens a ‘new paradigm’ for the design of stiff, fatigue-resistant rubbers in applications such as textured belts, tyre treads and soft robotics. A filled rubber is a composite […]

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Explosion at Indonesian nickel plant kills 19 workers

An explosion at a Chinese-owned nickel smelting plant on the Indonesian island of Sulawesi on 24 December has killed at least 19 people, and injured dozens more. The incident appears to be the latest in a series of safety failings in the area. According to local media reports, the deadly incident at the nickel smelter complex […]

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Computer vision accelerates self-driving reaction workups from being automated to autonomous

Researchers in Canada and the US have created a computer vision system for workup procedures. The platform monitors multiple visual changes during processes such as solvent exchange distillation, crystallisation, solid–liquid mixing and liquid–liquid extraction to advance the real-time response capacity of automated systems. Chemical research devotes significant time to monitoring and adjusting conditions of known […]

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